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Patient characteristics
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Overall (N = 225)
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No CVC malfunction (N = 163)
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CVC malfunction (N = 62)
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Treatment
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Rt-PA Group
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110 (48.9%)
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88 (54.0%)
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22 (35.5%)
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Heparin only Group
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115 (51.1%)
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75 (46.0%)
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40 (64.5%)
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Age -yr, mean ± SD
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63.2 (15.9)
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62.4 (16.6)
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65.4 (14.0)
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Female sex – no. (%)
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88 (39.1%)
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58 (35.6%)
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30 (48.4%)
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Duration of dialysis –yr, median (IQR)
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1.0 (0.0 - 6.0)
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1.0 (0.0 - 6.0)
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0.0 (0.0 - 1.0)
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Central venous catheter Indication - no. (%):
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Starting dialysis without peripheral access
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118 (52.4%)
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84 (51.5%)
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34 (54.8%)
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Failure of/awaiting peripheral access
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48 (21.3%)
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32 (19.6%)
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16 (25.8%)
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Catheter related infection
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14 (6.22%)
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11 (6.75%)
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3 (4.84%)
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First dialysis catheter ever - no. (%)
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137 (60.9%)
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99 (60.7%)
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38 (61.3%)
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Cause of end-stage renal disease:
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Diabetic nephropathy
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71 (31.6%)
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48 (29.4%)
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23 (37.1%)
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Glomerulonephritis
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17 (7.56%)
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12 (7.36%)
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5 (8.06%)
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Hypertension or vascular disease
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42 (18.7%)
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35 (21.5%)
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7 (11.3%)
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Coexisting or prior illness - no. (%):
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Diabetes mellitus
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124 (55.1%)
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86 (52.8%)
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38 (61.3%)
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Hypertension
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206 (91.6%)
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150 (92.0%)
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56 (90.3%)
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Ischemic heart disease
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47 (20.9%)
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34 (20.9%)
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13 (21.0%)
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Hemoglobin - g/liter, mean ± SD
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106 (15.7)
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106 (15.8)
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106 (15.4)
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Albumin – g/liter, mean ± SD
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32.1 (6.5)
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32.1 (6.7)
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32.0 (5.9)
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Platelet count - x10-9/litre, median (IQR)
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230 (185–293)
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233 (185–298)
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220 (183–283)
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- IQR: interquartile range; SD: standard deviation.
